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Zhao Cheng Selected Research

TG101209

9/2021The JAK2 inhibitor TG101209 exhibits anti-tumor and chemotherapeutic sensitizing effects on Burkitt lymphoma cells by inhibiting the JAK2/STAT3/c-MYB signaling axis.
12/2017The effect of the JAK2 inhibitor TG101209 against T cell acute lymphoblastic leukemia (T-ALL) is mediated by inhibition of JAK-STAT signaling and activation of the crosstalk between apoptosis and autophagy signaling.

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Zhao Cheng Research Topics

Disease

10Neoplasms (Cancer)
05/2022 - 11/2018
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022 - 12/2017
3COVID-19
01/2022 - 03/2021
3Inflammation (Inflammations)
01/2020 - 02/2011
3Diabetic Neuropathies (Diabetic Neuropathy)
01/2015 - 01/2013
2Fatigue
05/2022 - 04/2022
2Acute Promyelocytic Leukemia
05/2021 - 01/2019
2Disease Progression
10/2020 - 01/2019
2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
10/2020 - 12/2017
2Aortic Aneurysm (Aneurysm, Aortic)
12/2019 - 01/2015
2Colitis
01/2017 - 02/2011
2Heart Failure
01/2015 - 03/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
08/2022
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2022
1Hypoxia (Hypoxemia)
06/2022
1Necrosis
01/2022
1Carcinogenesis
01/2022
1Burkitt Lymphoma (Burkitt's Lymphoma)
09/2021
1Infections
03/2021
1Eosinophilia
07/2020
1Abdominal Aortic Aneurysm
01/2020
1Neoplasm Metastasis (Metastasis)
10/2019
1Lung Neoplasms (Lung Cancer)
01/2019
1Renal Cell Carcinoma (Grawitz Tumor)
11/2018
1Kidney Neoplasms (Kidney Cancer)
11/2018
1Hemorrhage
08/2017
1Hereditary Hemorrhagic Telangiectasia
08/2017
1Chromosome Aberrations (Chromosome Abnormalities)
08/2017
1Typhoid Fever (Typhoid)
08/2016
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2015
1Hypertension (High Blood Pressure)
01/2015
1Cardiovascular Diseases (Cardiovascular Disease)
01/2015
1Cardiac Arrhythmias (Arrythmia)
01/2015
1Nerve Degeneration
01/2013
1Wounds and Injuries (Trauma)
02/2011

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
01/2022 - 12/2017
4Pharmaceutical PreparationsIBA
01/2022 - 12/2017
2TG101209IBA
09/2021 - 12/2017
2Reactive Oxygen Species (Oxygen Radicals)IBA
05/2021 - 10/2020
2MicroRNAs (MicroRNA)IBA
01/2021 - 01/2015
2Angiotensin IIIBA
01/2020 - 12/2019
2Hemoglobins (Hemoglobin)IBA
08/2017 - 08/2017
2NAD (NADH)IBA
01/2013 - 01/2013
1Histones (Histone)IBA
08/2022
1Untranslated RNA (Noncoding RNA)IBA
08/2022
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
06/2022
1Agammaglobulinaemia Tyrosine KinaseIBA
06/2022
1TNF Receptor-Associated Factor 4IBA
01/2022
1Histone MethyltransferasesIBA
01/2022
1WastewaterIBA
01/2022
1Viral RNAIBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Biological ProductsIBA
01/2022
1B7-H1 AntigenIBA
11/2021
1CTLA-4 AntigenIBA
11/2021
1Immune Checkpoint ProteinsIBA
11/2021
1AntigensIBA
11/2021
1ArginaseIBA
11/2021
1Estrogen ReceptorsIBA
11/2021
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2021
1Complement System Proteins (Complement)IBA
03/2021
1Histone Deacetylases (Histone Deacetylase)IBA
10/2020
1Messenger RNA (mRNA)IBA
10/2020
1Lactate Dehydrogenase 5IBA
10/2020
1Nucleosomes (Nucleosome)IBA
07/2020
1BP-1-102IBA
01/2020
1Conditioned Culture MediaIBA
12/2019
1cinobufotalinIBA
10/2019
1CateninsIBA
10/2019
1Cisplatin (Platino)FDA LinkGeneric
10/2019
1LuciferasesIBA
10/2019
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2019
1UbiquitinIBA
01/2019
1flavoneIBA
11/2018
1scutellarinIBA
11/2018
1GlycosidesIBA
11/2018
1Beclin-1IBA
12/2017
1Janus Kinase InhibitorsIBA
12/2017
1IronIBA
08/2017
1EndoglinIBA
08/2017
1Smad Proteins (Mothers Against Decapentaplegic Homolog)IBA
08/2017
1Activin Receptors (Activin Receptor)IBA
08/2017
1Thalidomide (Thalomid)FDA Link
08/2017
1OxazoloneIBA
01/2017
1Attenuated VaccinesIBA
08/2016
1VaccinesIBA
08/2016
1Electron Transport Complex IV (Cytochrome c Oxidase)IBA
03/2013
1Mitochondrial DNA (mtDNA)IBA
03/2013
1Dextran SulfateIBA
02/2011

Therapy/Procedure

3Therapeutics
01/2019 - 12/2017
3Transplantation
01/2017 - 01/2013
2Esophagectomy
05/2022 - 04/2022
1Immunotherapy
01/2022
1Critical Care (Surgical Intensive Care)
01/2022
1Blood Transfusion (Blood Transfusions)
08/2017
1Splenectomy
02/2011